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32 The medical significance of the interaction is unclear at this time. Though facts are usually not readily available, the same reaction might take place with voriconazole. The two fluconazole and voriconazole are inhibitors of CYP3A4, the hepatic microsomal isoenzyme liable for metabolism of testosterone.[33]
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Its advantage compared to other testosterone derivatives is definitely the gradual rate of launch just after injection and for a longer time half-existence. It absolutely was made by the company Pharmacia and Upjohn and FDA approved on July twenty five, 1979.
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